Bustamante Lab Recent Publications List
2012
- L. Bintu, T. Ishibashi, M. Dangkulwanich, Y-Yi, Wu, L. Lubkowska, M. Kashlev & C. Bustamante
Nucleosomal Elements that Control the Topography of the Barrier to Transcription
Cell, November 9, Vol. 151, no. 4, 738-749
PDF
Disclaimer: This video was made for fun and does not reflect the dynamics of transcription from our scientific studies.
Animation
Video Abstract (Youtube)
- G. Chistol, S. Liu, C. L. Hetherington, J. R. Moffitt, S. Grimes, P. J. Jardine, C. Bustamante
High Degree of Coordination and Division of Labor Among Subunits in a Homomeric Ring ATPase
Cell, November 21, Vol. 151, no. 5, 1017-1028
PDF
- SangHyuk Lee, Jae Yen Shin, Antony Lee & Carlos Bustamante
Counting single photoactivatable fluorescent molecules by photoactivated localization microscopy (PALM)
PNAS October 23, 2012 vol. 109 no. 43 17436-17441 PDF
- Xiaohui Qu, Laura Lancaster, Harry F. Noller, Carlos Bustamante & Ignacio Tinoco Jr.
Ribosomal protein S1 unwinds double-stranded RNA in multiple steps
PNAS September 4 vol. 109 no.36 14458-14463 PDF
- Zamft, B, Bintu L, Ishibashi, T, and Bustamante C
Nascent RNA Structure modules the transcription dynamics of RNA Polymerases
PNAS June 5, 2012 vol. 109 no.23 8949-8953 PDF
- Craig L. Hetherington, Jeffrey R. Moffitt, Paul J. Jardine, & Carlos Bustamante
Viral DNA Packaging Motors in Comprehensive Biophysics
(Academic Press, May 17, 2012), vol. 4, pp. 420-446
- Phillip J. Elms, John D. Chodera, Carlos Bustamante and Susan Marqusee
The Molten globule state is unusually deformable under mechanical force
PNAS March 6, 2012 vol 109 no 10 3796-3801 PDF
2011
- Christian M. Kaiser, Daniel Goldman, John D. Chodera, Ignacio Tinoco Jr., & Carlos Bustamante
The Ribosome Modulates Nascent Protein Holding
Science Vol. 334 no 6063 pp. 1723-1727 (December 2011) PDF
- Lacramioara Bintu, Marta Kopaczynska, Courtney Hodges, Lucyna Lubkowska, Mikhail Kashlev & Carlos Bustamante
The elongation rate of RNA polymerase determines the fate of transcribed nucleosomes
Nature Structural & Molecular Biology
Vol. 18 pp. 1394-1399 (September 2011) PDF
PDF-supplement
- Wei Cheng, Srikesh G. Arunajadai, Jeffrey R. Moffitt, Ignacio Tinoco Jr. & Carlos Bustamante
Single-Base Pair Unwinding and Asynchronous RNA Release By the Hepatitis C Virus NS3 Helicase
Science Vol. 333 no. 6050 pp. 1746-1749 (September 2011) PDF
- Xiohui Qu, Jin-Der Wen, Laura Lancaster, Harry F. Noller, Carlos Bustamante & Ignacio Tinoco Jr.
The ribosome uses two active mechanisms to unwind messenger RNA during translation
Nature 475, 118-121 (7 July 2011) PDF
- Rodrigo A. Maillard, Gheorghe Chistol, Maya Sen, Maurizio Righini, Jiongyi Tan, Christian M. Kaiser, Courtney Hodges, Andreas Martin & Carlos Bustamante
ClpX(P) Generates Mechanical Force to Unfold and Translocate Its Protein Substrates
Cell, Volume 145, Issue 3, 459-469 (29 April 2011) PDF
Cell Preview, Commentary
- Carlos Bustamante, Wei Cheng, & Yara Mejia
Revisiting the Central Dogma One Molecule at a Time
Cell, Volume 144, Issue 4, 480-497, (18 February 2011) PDF
- Sudhanshu B, Mihardja S, Koslover EF, Mehraeen S, Bustamante C, and Spakowitz AJ
Tension-dependent structural deformation alters single-molecule transition kinetics
PNAS February 1, 2011 vol. 108 no. 5 1885-1890 PDF
2010
- Carlos Bustamante and Jeffrey R. Moffitt
Viral DNA Packaging: One Step at a Time
Single Molecule Spectroscopy in Chemistry, Physics and Biology; Springer Series in Chemical Physics, 2010, Vol 96, Part 5, 237-269 PDF
- Hagar Zohar, Craig L. Hetherington, Carlos Bustamante & Susan J. Muller
Peptide Nucleic Acids as Tools for Single-Molecule Sequence Detection and Manipulation
American Chemical Society, Nano Lett., 2010, 10 (11), pp 4697-4701 PDF
- Jin Yu, Wei Cheng, Carlos Bustamante & George Oster
Coupling Translocation with Nucleic Acid Undwinding by NS3 Helicase
J. Molecular Biology, September 29,vol. 404, 439-455 PDF
- Jeffrey R. Moffitt, Yann R. Chemla, & Carlos Bustamante
Mechanistic constraints from the substrate concentration dependence of enzymatic fluctuations
PNAS, September 7,vol. 107, no 36, 15739-15744 PDF
PDF-supplement
- Jeffrey R. Moffitt, Yann R. Chemla, & Carlos Bustamante
Methods in Statistical Kinetics
Methods in Enzymology, vol. 475: 221-257 PDF
- Josep M. Hugueta, Cristiano V. Bizarroa, Nœria Fornsa, Steven B. Smith, Carlos Bustamante & Felix Ritort
Single-molecule derivation of salt dependent base-pair free energies in DNA
PNAS, August 31, 2010, vol. 107, no 35, 15431-15436 PDF
- Gang Chen, Kung-Yao Chang, Ming Yuan Chou, Carlos Bustamante & Ignacio Tinoco, Jr.
Triplex structures in an RNA pseudoknot enchance mechanical stability and increase efficiency of -1 ribosomal frameshifting
PNAS, August 4, 2009 vol. 106 no. 31, 12706-12711 PDF
- Tinya C. Flemming, Jae Yen Shin, Sang-Hyuk Lee, Eric Becker, Kerwyn Casey Huang, Carlos Bustamante & Kit Pogliano
Dynamic SpoIIIE assembly mediates septal membrane fission during Bacillus
subtilis sporulation
Genes Dev. June 2010 24: 1160-1172 PDF
- Jin Yu, Jeffrey Moffitt, Craig L. Hetherington, Carlos Bustamante and George Oster
Mechanochemistry of a Viral DNA Packaging Motor
Journal of Molecular Biology 400, 186-203 PDF
- Elizabeth A. Shank, Ciro Cecconi, Jesse W. Dill, Susan Marqusee & Carlos Bustamante
The folding cooperativity of a protein is controlled by its chain topology
Nature 465, 637-640 (3 June 2010)
PDF
2009
- K. Aathavan, Adam T. Politzer, Ariel Kaplan, Jeffrey R. Moffitt, Yann R. Chemla, Shelley Grimes, Paul J. Jardine, Dwight L. Anderson, & Carlos Bustamante
Substrate interactions and promiscuity in a viral DNA packaging motor
Nature 461, 669-673 (1 October 2009)
PDF
PDF-supplement
- Borja Ibarra, Yann R Chemla, Sergey Plyasunov, Steven B Smith, José M Lázaro, Margarita Salas and Carlos Bustamante
Proofreading dynamics of a processive DNA polymerase
The EMBO Journal (2009) 28, 2794-2802
PDF
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Courtney Hodges, Lacramioara Bintu, Lucyna Lubkowska, Mikhail Kashlev, Carlos Bustamante
Nucleosomal Fluctuations Govern the Transcription Dynamics of RNA Polymerase II
Science 31 July 2009: Vol. 325 no. 5940 pp. 626-628
PDF,
Online Supplement
Science Perspective,
Online Commentary
- Galburt E.A, Grill S, and C. Bustamante
Single molecule transcription elongation
Methods (2009), doi:10.1016/j.meth 2009.04.021
PDF
- Mangiarotti L, Cellai S, Ross W, Bustamante C, Rivetti C.
Sequence-dependent upstream DNA-RNA polymerase interactions in the open complex with lambdaPR and lambdaPRM promoters and implications for the mechanism of promoter interference
J Mol Biol. 2009 Jan 23;385(3):748-60. Epub 2008 Nov 24.
PDF
- Moffitt, JR, Chemla, YR, Aathavan, K, Grimes, S, Jardine, PJ, Anderson, DL, and C. Bustamante
Intersubunit coordination in a homomeric ring ATPase
Nature 457, 446-450 (22 January 2009).
PDF
PDF-supplement
2008
- Alcaraz J, Xu R, Mori H, Nelson CM, Mroue R, Spencer VA, Brownfield D, Radisky DC, Bustamante C, & Bissell MJ
Laminin and biomimetic extracellular elasticity enchance functional differentiation in mammary epithelia
EMBO J. 2008 Nov 5;27(21):2829-38. Epub 2008 Oct 9 PDF
- Mejia, YX, Mao, H, Forde, NR, and C. Bustamante
Thermal Probing of E.coli RNA Polymerase
Journal of Molecular Biology 382, 628 (2008).
PDF
- Ciro Cecconi, Elizabeth A. Shank, Frederick W. Dahlquist, Susan Marqusee, & Carlos Bustamante
Protein-DNA chimeras for single molecule mechanical folding studies with the optical tweezers
European Biophysics Journal, Vol. 37, 6 (2008).
PDF
- Maragakis, P. Ritort, F. Bustamante, C. Karplus, M., and G.E. Crooks,
Bayesian estimates of free energies from nonequilibrium work data in the presence of instrument noise
The Journal of Chemical Physics 129, 024102 (2008).
PDF
- C. Bustamante.
In singulo Biochemistry: When Less is More
Annual Review of Biochemistry 77, 45-50 (2008)
PDF
- C. Bustamante
Physical Biology at the Crossroads,
ch. 5 in Physical Biology: From Atoms to Medicine, Ahmed Zewail, ed. Pps. 115-135, Imperial College Press: London (2008).
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Ptacin, J.L., Nöllmann, M., Becker, E.C., Cozzarelli, N.R., Pogliano, K., and C. Bustamante,
Sequence-directed DNA export guides chromosome translocation during sporulation in Bacillus subtilis
Nat Struct Mol Biol. Nat. Struct. Mol. Biol. 15(5), 485-493 (May, 2008).
PDF
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Wen, J-D., Lancaster, L., Hodges, C., Zeri, A-C., Yoshimura, S-H., Noller, H.F., Bustamante, C., and I. Tinoco, Jr.,
Following translation by single ribosomes one codon at a time
Nature 452, 598-603 (2008)
PDF
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Chemla, Y.R., Moffitt, J.R., and C. Bustamante
Exact Solutions for Kinetic Models of Macromolecular Dynamics
J. Phys. Chem. B 112(19), 6025 -6044 (2008)
PDF
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Moffitt, J.R., Chemla, Y.R., Smith, S.B., and C. Bustamante,
Recent Advances in Optical Tweezers
Annual Review of Biochemistry (2008) 77, 205-228 (2008).
PDF
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Green, L., Kim, CH., Bustamante, C., and I Tinoco, Jr.,
Characterization of the Mechanical Unfolding of RNA pseudoknots
J. Mol. Biol, 375(2):511-28 (2008, Epub 2007)
PDF
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Bustamante, C., Chemla, Y.R., and J.R. Moffitt,
High-Resolution Dual-Trap Optical Tweezers with Differential Detection
Ch 14 in Single-Molecule Techniques: A Laboratory Manual. P. Selvin and T. Ha, Eds. (CSHL, 2008)
2007
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Cecconi, C., Shank, E.A., Marqusee, S., and C. Bustamante,
Studying Protein Folding with Laser Tweezers
Proceedings of the International School Enrico Fermi, Società Italiana di Fisica: pps 145-160 (October, 2007).
PDF
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Downing, K., Comolli, L.R., Spakowitz, A.J., Siegerist, C.E., Jardine, P.J., Grimes, S., Anderson, D.L., and C. Bustamante,
Three-Dimensional Architecture of the Bacteriophage phi 29 Packaged Genome and Elucidation of its Packaging Process
Virology 371(2), 267-277 (2008, Epub 2007)
PDF
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Vieregg, J., Cheng, W., Bustamante, C., and I. Tinoco, Jr.
Measurement of the Effect of Monovalent Cations on RNA Hairpin Stability
J. Am. Chem. Soc. 129(48), 4966-14973 (2007).
PDF
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Tang, M., Cecconi, C., Bustamante, C., and D.C. Rio
Analysis of P element transposase protein-DNA interactions during early stages of transposition
J. Biol. Chem. 282(39), 29002-12 (2007).
PDF
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Cheng, W., Dumont, S., Tinoco, I. Jr., and C. Bustamante.
NS3 helicase actively separates RNA strands and senses sequence barriers ahead of the opening fork
PNAS 104(35), 13954-13959 (2007).
PDF
[SCIENCE commentary]
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Choy JL, Parekh SH, Chaudhuri O, Liu AP, Bustamante C, Footer MJ, Theriot JA, Fletcher DA.
Differential force microscope for long time-scale biophysical measurements
Rev Sci Instrum, 78(4):043711 (April 2007)
PDF
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Pan T. X. Li, Carlos Bustamante, and Ignacio Tinoco, Jr.,
Real-time control of the energy landscape by force directs the folding of RNA molecules
PNAS, 104(17):7039-7044 (April 24, 2007, published online April 16, 2007).
PDF
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Eric A. Galburt, Stephan W. Grill, Anna Wiedmann, Lucyna Lubkowska, Jason Choy, Eva Nogales, Mikhail Kashlev, and Carlos Bustamante
Backtracking determines the force sensitivity of RNAP II in a factor-dependent manner
Nature, 446(7137):820-823 (April 12, 2007: Advance Online Publication March 14 2007).
PDF
[Supplementary Information]
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Marcelo Nöllmann, Michael D Stone, Zev Bryant, Jeff Gore, Nancy J Crisona, Seok-Cheol Hong, Sylvain Mitelheiser, Anthony Maxwell, Carlos Bustamante and Nicholas R Cozzarelli
Multiple modes of Escherichia coli DNA gyrase activity revealed by force and torque
Nature Structural and Molecular Biology, 14(4):264-271 (April 2007)
PDF [Supplementary data/Info]
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Leschziner AE, Saha A, Wittmeyer J, Zhang Y, Bustamante C, Cairns BR, Nogales E.
Conformational flexibility in the chromatin remodeler RSC observed by electron microscopy and the orthogonal tilt reconstruction method
PNAS,104(12):4913-4918 (March 20, 2007).
PDF
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Wen JD, Manosas M, Li P, Smith S, Bustamante C, Ritort F, Tinoco Jr I.
Force unfolding kinetics of RNA using optical tweezers. I. Effects of experimental variables on measured results
Biophys J. 92:2996-3009 (May 2007), published online Feb 9.
PDF
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Manosas M, Wen JD, Li P, Smith S, Bustamante C, Tinoco Jr I, Ritort F.
Force unfolding kinetics of RNA using optical tweezers. II. Modeling experiments
Biophys J. 92:3010-3021 (May 2007), published online Feb 9.
PDF
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Thorsten Hugel, Jens Michaelis, Craig L. Hetherington, Paul J. Jardine, Shelley Grimes, Jessica M. Walter, Wayne Falk, Dwight L. Anderson and Carlos Bustamante
Experimental Test of Connector Rotation during DNA Packaging into Bacteriophage phi29 Capsids
PLoS Biology, (4 March 2007)
Online
[Online Commentary]
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Jessica M. Walter, Derek Greenfield, Carlos Bustamante, and Jan Liphardt
Light-powering Escherichia coli with proteorhodopsin
PNAS, 104: 2408-2412 (2007)
PDF
Online Commentary:
1,
2,
3,
4,
5,
6.
2006
-
Ignacio Tinoco Jr., Pan T. X. Li and Carlos Bustamante
Determination of thermodynamics and kinetics of RNA reactions by force
Quarterly Reviews of Biophysics 39(4):325-360 (November 2006).
PDF
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Jerod L. Ptacin, Marcelo Nöllmann, Carlos Bustamante and Nicholas Cozzarelli
Identification of the FtsK sequence-recognition domain
Nature Structural and Molecular Biology 13: 1023-1025 (2006)
PDF
Supplementary Information:
materials and methods,
data,
figure 3,
figure 2,
figure 1,
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Yongli Zhang, Corey L. Smith, Anjanabha Saha, Stephan W. Grill, Shirley Mihardja, Steven B. Smith, Bradley R. Cairns, Craig L. Peterson, Carlos Bustamante
DNA Translocation and Loop Formation Mechanism of Chromatin Remodeling by SWI/SNF and RSC
Molecular Cell 24: 559-568 (2006)
PDF
Summary from Cell
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Mihardja S, Spakowitz A, Zhang Y, Bustamante C
Effect of force on mononucleosomal dynamics
PNAS 103 (43): 15871-15876 (2006)
PDF
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Li P XT, Bustamante C, Tinoco I Jr.
Unusual mechanical stability of a minimal RNA kissing complex
PNAS 103: 15847-15852 (2006)
PDF
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Gore J, Bryant Z, Nöllmann M, Le MU, Cozzarelli NR, Bustamante C
DNA overwinds when stretched
Nature 442: 836-839 (2006)
PDF
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Moffitt JR, Chemla YR, Izhaky D, Bustamante C
Differential detection of dual traps improves
the spatial resolution of optical tweezers
PNAS, 103 (24): 9006-11 (2006) PDF
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Ritort F, Mihardja S, Smith
SB, Bustamante C
Condensation transition in DNA-polyaminoamide
dendrimer fibers studied using optical tweezers
Phys. Rev. Lett. 96 (11): 118301-4 (2006)
PDF
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Gore J, Bryant Z, Stone MD,
Nöllmann M, Cozzarelli NR and Bustamante C
Mechanochemical analysis of DNA gyrase using rotor
bead tracking
Nature 439: 100-104 (2006) PDF
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Dumont S, Cheng W, Serebrov
V, Beran RK, Tinoco I Jr., Pyle AM and Bustamante C
RNA translocation and unwinding mechanism of HCV NS3 helicase and
its coordination by ATP
Nature 439: 105-108 (2006) PDF
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Li PT, Collin D, Smith SB,
Bustamante C, Tinoco I Jr.
Probing the mechanical folding kinetics of TAR
RNA by hopping, force-jump, and force-ramp methods
Biophysics Journal, 90 (1): 250-60 (2006) PDF
2005
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Bustamante C
Unfolding single RNA molecules: bridging the gap between equilibrium and non-equilibrium statistical thermodynamics.
Quarterly Reviews of Biophysics, 38(4):291-301 (November 2005, published online in 2006)
PDF
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O
Levy, JL Ptacin, PJ Pease, J Gore, MB Eisen, C Bustamante, and NR
Cozzarelli
Identification of oligonucleotide sequences that
direct the movement of the Escherichia coli FtsK translocase
PNAS, 102 (49):17618 - 17623 (2005)
PDF
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Gorostiza
P, Tombola F, Verdaguer A, Smith SB, Bustamante C, Isacoff EY
Molecular handles for the mechanical
manipulation of single-membrane proteins in living cells
IEEE Trans Nanobioscience. 4 (4): 269-76 (2005) PDF
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J Martinez, TD Yuzvinsky, AM
Fennimore, A Zettl, R Garcia 3 and C Bustamante
Length control and sharpening of atomic force
microscope carbon nanotube tips assisted by an electron beam.
Nanotechnology, 16, 2493 - 2496 (September 2005) PDF
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Wilcox AJ, Choy J, Bustamante
C, and Matouschek A
Effect of protein structure on mitochondrial
import
PNAS 102 (43): 15435 - 15440 OCT 25 (2005) PDF
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Brown TA, Cecconi C, Tkachuk
AN, Bustamante C, and Clayton DA
Replication of mitochondrial DNA occurs by
strand displacement with alternative light-strand origins, not via a
strand-coupled mechanism
Genes & Development 19 (20): 2466-2476 OCT 15 (2005) PDF
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Mao HB, Arias-Gonzalez JR,
Smith SB, Tinoco I, and Bustamante C
Temperature control methods in a laser
tweezers system
Biophysical Journal 89 (2): 1308-1316 AUG (2005) PDF
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Bustamante C, Liphardt J, Ritort F
The nonequilibrium thermodynamics of small
systems
Physics Today 58 (7): 43-48 JUL (2005) PDF
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Tang M, Cecconi C, Kim H,
Bustamante C, and Rio DC
Guanosine triphosphate acts as a cofactor to
promote assembly of initial P-element transposase-DNA synaptic
complexes
Genes & Development 19 (12): 1422-1425 JUN 15 (2005)
PDF
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Cecconi C, Shank EA,
Bustamante C, and Marqusee S
Direct Observation of the Three-State Folding of a
Single Protein Molecule
Science 23: 2057-2060 (2005)
PDF
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Chemla YR, Aathavan K, Michaelis J, Grimes S, Jardine PJ, Anderson
DL and Bustamante C
Mechanism of Force Generation of a Viral
DNA Packaging Motor
Cell 122 (5): 683-692 (2005)
PDF
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Collin D, Ritort F, Jarzynski
C, Smith SB, Tinoco (Jr) I, and Bustamante C
Verification of the Crooks fluctuation theorem
and recovery of RNA folding free energies
Nature 437: 231-234 (2005) PDF
(see accompanying Nature News and
Views article)
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Paul J. Pease, Oren Levy,
Gregory J. Cost, Jeff Gore, Jerod L. Ptacin, David Sherratt, Carlos
Bustamante, and Nicholas R. Cozzarelli
Sequence-Directed DNA Translocation by
Purified FtsK
Science 307: 586-590 (2005) PDF REPRINT (see News
& Views in NSMB)
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Gu Li, Marcia Levitus, Carlos
Bustamante & Jonathan Widom
Rapid spontaneous accessibility of nucleosomal
DNA
Nature Structural & Molecular Biology 12, 46 - 53 (2005) PDF
2004
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Bustamante C
Of torques, forces and protein
machines.
Protein Sci. 2004 13(11): 3061-3065 (2004) PDF
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Trepagnier EH, Jarzynski C,
Ritort F, Crooks GE, Bustamante C, and Liphardt J
Experimental Test of Hatano and Sasa's
Nonequilibrium Steady-state Equality
PNAS 101 (42) 15038-15041 (2004) PDF
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Bustamante C, Chemla YR,
Forde NR & Izhaky D
Mechanical processes in biochemistry
Annual Review of Biochemistry (2004) 73: 705-748 PDF
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Goedken ER, Levitus M,
Johnson A, Bustamante C, O'Donnell M, Kuriyan J
Fluorescence measurements on the E-coli DNA
polymerase clamp loader:
Implications for conformational changes during ATP and clamp
binding
Journal Of Molecular Biology 336 (5): 1047-1059 (MAR 5 2004) PDF
2003
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Gore J, Ritort F & Bustamante C
Bias and error in estimates of equilibrium free-energy differences from nonequilibrium measurements
Proc Natl Acad Sci U S A (2003) 100: 12564-12569 PDF
(see accompanying PNAS Commentary)
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Matouschek A & Bustamante
C
Finding a protein's Achilles heel
Nat Struct Biol. (2003) 10(9):674-6 PDF
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Bryant Z, Stone MD, Gore J, Smith SB,Cozzarelli NR Bustamante C
Structural transitions and elasticity from
torque measurements on DNA
Nature (2003) 424: 338-341 PDF
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Stone MD, Bryant Z, Crisona
NJ, Smith SB, Vologodskii A, Bustamante C, and Cozzarelli NR
Chirality sensing by Escherichia coli
topoisomerase IV and the mechanism of type II topoisomerases
Proc Natl Acad Sci U S A (2003) 100: 8654-8659 PDF
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Smith SB, Cui Y, Bustamante C.
Optical-Trap Force Transducer that Operates by
Direct Measurement of Light Momentum
Methods in Enzymology (2003), 361:134-162 PDF
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Onoa B, Dumont S, Liphardt J, Smith SB, Tinoco, I Jr., Bustamante C
Identifying the kinetic barriers to mechanical
unfolding of the T. thermophila ribozyme
Science (2003): 1892-1895 PDF
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Rivetti C, Codeluppi S.,
Dieci G.and Bustamante C
Visualizing RNA Extrusion and DNA Wrapping in
Transcription Elongation Complexes of Bacterial and Eukaryotic RNA
Polymerases
J. Mol. Bio. (2003) 5:1413-1426 PDF
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Keller D, Swigon D, Bustamante C
Relating Single-Molecule Measurements to
Thermodynamics
Biophys. J. (2003) 84: 733-738 PDF
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Bustamante C, Bryant Z, Smith
SB
Ten years of tension: single-molecule DNA
mechanics
Nature (2003) 421: 423 - 427 PDF
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Kellermayer MSZ, Bustamante C,
Granzier HL
Mechanics and structure of titin oligomers
explored with atomic force microscopy
Biochimica Et Biophysica Acta-Bioenergetics 1604 (2): 105-114 (JUN 5 2003)
PDF
2002
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Tinoco I Jr., Bustamante, C
The effect of force on thermodynamics and
kinetics of single molecule reactions
Biophysical Chemistry (2002) 102: 513-533 PDF
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Ritort F, Bustamante C,
Tinoco I Jr
A two-state kinetic model for the unfolding of
single molecules by mechanical force.
Proc Natl Acad Sci U S A (2002) 99:13544-8 PDF
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Forde NR, Izhaky D, Woodcock GR, Wuite GJ, Bustamante C
Using mechanical force to probe the mechanism
of pausing and arrest during continuous elongation by Escherichia coli RNA
polymerase.
Proc Natl Acad Sci U S A (2002) 99:11682-7 PDF
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Liphardt J, Dumont S, Smith SB, Tinoco I Jr, Bustamante C
Equilibrium information from nonequilibrium
measurements in an experimental test of Jarzynski's equality.
Science (2002) 296:1832-5 PDF
-
Parak WJ, Gerion D, Zanchet
D, Woerz AS, Pellegrino T, Micheel C, Williams SC, Seitz M, Bruehl RE,
Bryant Z, Bustamante C, Bertozzi CR, Alivisatos AP
Conjugation of DNA to silanized colloidal
semiconductor nanocrystalline quantum dots
Chemistry Of Materials 14 (5): 2113-2119 (MAY 2002) PDF
2001
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Smith DE, Tans SJ, Smith SB, Grimes S, Anderson DL, Bustamante C
The bacteriophage phi29 portal motor
can package DNA against a large internal force
Nature (2001) 413:748-52 (October 2001) PDF
[Supplementary Info]
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Bustamante C, Keller D, Oster G
The physics of molecular motors.
Acc Chem Res (2001) 34:412-20 PDF
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d'Erme M, Yang G, Sheagly E,
Palitti F, Bustamante C
Effect of poly(ADP-ribosyl)ation and Mg2+ ions
on chromatin structure revealed by scanning force microscopy.
Biochemistry (2001) 40:10947-55 PDF
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Liphardt J, Onoa B, Smith SB,
Tinoco I JR, Bustamante C
Reversible unfolding of single RNA molecules
by mechanical force.
Science (2001) 292:733-7 PDF
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Kellermayer MS, Smith SB,
Bustamante C, Granzier HL
Mechanical fatigue in repetitively stretched
single molecules of titin.
Biophys J (2001) 80:852-63 PDF
2000
-
Keller D., and Bustamante C.
The Mechanochemistry of Molecular Motors
Biophys. J. 78: 541-556, (2000)
PDF
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Bustamante C, Macosko JC, Wuite GJ
Grabbing the cat by the tail: manipulating
molecules one by one.
Nat Rev Mol Cell Biol (2000) 1:130-6 PDF
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Wuite GJ, Smith SB, Young M,
Keller D, Bustamante C
Single-molecule studies of the effect of
template tension on T7 DNA polymerase activity.
Nature (2000) 404:103-6 PDF
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Kellermayer MS, Smith S, Bustamante
C, Granzier HL
Mechanical manipulation of single titin
molecules with laser tweezers.
Adv Exp Med Biol (2000) 481:111-26; discussion 127-8
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Wuite GJ, Davenport RJ,
Rappaport A, Bustamante C
An integrated laser trap/flow control video
microscope for the study of single biomolecules.
Biophys J (2000) 79:1155-67 PDF
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Baumann CG, Bloomfield VA, Smith SB, Bustamante C, Wang MD,
Block SM
Stretching of single collapsed DNA molecules.
Biophys J (2000) 78:1965-78 PDF
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Davenport RJ, Wuite GJ,
Landick R, Bustamante C
Single-molecule study of transcriptional
pausing and arrest by E. coli RNA polymerase.
Science (2000) 287:2497-500 PDF
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Yang GL, Cecconi C, Baase WA,
Vetter IR, Breyer WA, Haack, JA, Matthews BW, Dahlquist FW, Bustamante C
Solid-state synthesis and mechanical unfolding
of polymers of T4 lysozyme.
Proc. Nat. Acad. Sci., 2000, V97(N1):139-144 PDF
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Cui Y, Bustamante C
Pulling a single chromatin fiber reveals the
forces that maintain its higher-order structure.
Proc Natl Acad Sci U S A (2000) 97(1):127-32 PDF
1999
-
Tinoco I, Bustamante C
How RNA folds
J. Mol. Biol., 1999, V293(N2):271-281 PDF
-
Leuba SH, Bustamante C
Analysis of chromatin by scanning force
microscopy
Methods Mol Biol (1999) 119:143-60